TIL: Signs of cirrhosis - the hands
JAMA released this meta-analysis1 in 2012 detailing what physical exam and laboratory findings were associated with cirrhosis (end-stage liver disease). I was unsurprised to find that ascites, thrombocytopenia, and spider nevi were the most consistently studied findings with high likelihood ratios (LR) for a patient to have cirrhosis. I was surprised that Terry's nails had LRs of 16-22 in the two studies looking at those.
By Hojasmuertas - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=22101599
1. Udell, Jacob A., et al. "Does this patient with liver disease have cirrhosis?." Jama 307.8 (2012): 832-842.
